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Contributors
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- By Ted Abel, Antoine Adamantidis, Karla V. Allebrandt, Simon N. Archer, Amelie Baud, Michel Billiard, Carlos Blanco-Centurion, Diane B. Boivin, Ethan Buhr, Matthew E. Carter, Nicolas Cermakian, Jennifer H.K. Choi, S.Y. Christin Chong, Chiara Cirelli, Marc Cuesta, Thomas Curie, Yves Dauvilliers, Luis de Lecea, Derk-Jan Dijk, Stephane Dissel, Annette C. Fedson, Jonathan Flint, Marcos G. Frank, Paul Franken, Ying-Hui Fu, Thorarinn Gislason, David Gozal, Devon A. Grant, Hakon Hakonarson, Makoto Honda, Hyun Hor, Christer Hublin, Peng Jiang, Takashi Kanbayashi, Jaakko Kaprio, Andrew Kasarskis, Leila Kheirandish-Gozal, RodaRani Konadhode, Michael Lazarus, Meng Liu, Michael March, Mark F. Mehler, Keivan Kaveh Moghadam, Valérie Mongrain, Charles M. Morin, Benjamin M. Neale, Seiji Nishino, Allan I. Pack, Dheeraj Pelluru, Rosa Peraita-Adrados, Giuseppe Plazzi, David A. Prober, Louis J. Ptáček, Irfan A. Qureshi, David M. Raizen, John J. Renger, Till Roenneberg, Elizabeth J. Rossin, Takeshi Sakurai, Paul Salin, Karen D. Schilli, Eva C. Schulte, Laurent Seugnet, Paul J. Shaw, Priyattam J. Shiromani, Patrick Sleiman, Mehdi Tafti, Joseph S. Takahashi, Matthew S. Thimgan, Katsushi Tokunaga, Giulio Tononi, Fred W. Turek, Yoshihiro Urade, Hans P.A. Van Dongen, Juliane Winkelmann, Christopher J. Winrow
- Edited by Paul Shaw, Mehdi Tafti, Michael J. Thorpy
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- Book:
- The Genetic Basis of Sleep and Sleep Disorders
- Published online:
- 05 November 2013
- Print publication:
- 24 October 2013, pp xi-xiv
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Anticipated Behaviors of Emergency Prehospital Medical Care Providers during an Influenza Pandemic
- Vivienne C. Tippett, Kerrianne Watt, Steven G. Raven, Heath A. Kelly, Michael Coory, Frank Archer, Konrad Jamrozik
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- Journal:
- Prehospital and Disaster Medicine / Volume 25 / Issue 1 / February 2010
- Published online by Cambridge University Press:
- 28 June 2012, pp. 20-25
- Print publication:
- February 2010
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Introduction:
Emergency prehospital medical care providers are frontline health workers during emergencies. However, little is known about their attitudes, perceptions, and likely behaviors during emergency conditions. Understanding these attitudes and behaviors is crucial to mitigating the psychological and operational effects of biohazard events such as pandemic influenza, and will support the business continuity of essential prehospital services.
Problem:This study was designed to investigate the association between knowledge and attitudes regarding avian influenza on likely behavioral responses of Australian emergency prehospital medical care providers in pandemic conditions.
Methods:Using a reply-paid postal questionnaire, the knowledge and attitudes of a national, stratified, random sample of the Australian emergency prehospital medical care workforce in relation to pandemic influenza were investigated. In addition to knowledge and attitudes, there were five measures of anticipated behavior during pandemic conditions: (1) preparedness to wear personal protective equipment (PPE); (2) preparedness to change role; (3) willingness to work; and likely refusal to work with colleagues who were exposed to (4) known and (5) suspected influenza. Multiple logistic regression models were constructed to determine the independent predictors of each of the anticipated behaviors, while controlling for other relevant variables.
Results:Almost half (43%) of the 725 emergency prehospital medical care personnel who responded to the survey indicated that they would be unwilling to work during pandemic conditions; one-quarter indicated that they would not be prepared to work in PPE; and one-third would refuse to work with a colleague exposed to a known case of pandemic human influenza.
Willingness to work during a pandemic (OR = 1.41; 95% CI = 1.0−1.9), and willingness to change roles (OR = 1.44; 95% CI = 1.04−2.0) significantly increased with adequate knowledge about infectious agents generally. Generally, refusal to work with exposed (OR = 0.48; 95% CI = 0.3−0.7) or potentially exposed (OR = 0.43; 95% CI = 0.3−0.6) colleagues significantly decreased with adequate knowledge about infectious agents. Confidence in the employer's capacity to respond appropriately to a pandemic significantly increased employee willingness to work (OR = 2.83; 95% CI = 1.9−4.1); willingness to change roles during a pandemic (OR = 1.52; 95% CI = 1.1−2.1); preparedness to wear PPE (OR = 1.68; 95% CI = 1.1−2.5); and significantly decreased the likelihood of refusing to work with colleagues exposed to (suspected) influenza (OR = 0.59; 95% CI = 0.4−0.9).
Conclusions:These findings indicate that education and training alone will not adequately prepare the emergency prehospital medical workforce for a pandemic. It is crucial to address the concerns of ambulance personnel and the perceived concerns of their relationship with partners in order to maintain an effective prehospital emergency medical care service during pandemic conditions.
Attitudes to Living and Working in Pandemic Conditions among Emergency Prehospital Medical Care Personnel
- Kerrianne Watt, Vivienne C. Tippett, Steven G. Raven, Konrad Jamrozik, Michael Coory, Frank Archer, Heath A. Kelly
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- Journal:
- Prehospital and Disaster Medicine / Volume 25 / Issue 1 / February 2010
- Published online by Cambridge University Press:
- 28 June 2012, pp. 13-19
- Print publication:
- February 2010
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Introduction:
Little is known about the risk perceptions and attitudes of healthcare personnel, especially of emergency prehospital medical care personnel, regarding the possibility of an outbreak or epidemic event.
Problem:This study was designed to investigate pre-event knowledge and attitudes of a national sample of the emergency prehospital medical care providers in relation to a potential human influenza pandemic, and to determine predictors of these attitudes.
Methods:Surveys were distributed to a random, cross-sectional sample of 20% of the Australian emergency prehospital medical care workforce (n = 2,929), stratified by the nine services operating in Australia, as well as by gender and location. The surveys included: (1) demographic information; (2) knowledge of influenza; and (3) attitudes and perceptions related to working during influenza pandemic conditions. Multiple logistic regression models were constructed to identify predictors of pandemic-related risk perceptions.
Results:Among the 725 Australian emergency prehospital medical care personnel who responded, 89% were very anxious about working during pandemic conditions, and 85% perceived a high personal risk associated with working in such conditions. In general, respondents demonstrated poor knowledge in relation to avian influenza, influenza generally, and infection transmission methods. Less than 5% of respondents perceived that they had adequate education/training about avian influenza. Logistic regression analyses indicate that, in managing the attitudes and risk perceptions of emergency prehospital medical care staff, particular attention should be directed toward the paid, male workforce (as opposed to volunteers), and on personnel whose relationship partners do not work in the health industry.
Conclusions:These results highlight the potentially crucial role of education and training in pandemic preparedness. Organizations that provide emergency prehospital medical care must address this apparent lack of knowledge regarding infection transmission, and procedures for protection and decontamination. Careful management of the perceptions of emergency prehospital medical care personnel during a pandemic is likely to be critical in achieving an effective response to a widespread outbreak of infectious disease.
The case for strategic international alliances to harness nutritional genomics for public and personal health†
- Jim Kaput, Jose M. Ordovas, Lynnette Ferguson, Ben van Ommen, Raymond L. Rodriguez, Lindsay Allen, Bruce N. Ames, Kevin Dawson, Bruce German, Ronald Krauss, Wasyl Malyj, Michael C. Archer, Stephen Barnes, Amelia Bartholomew, Ruth Birk, Peter van Bladeren, Kent J. Bradford, Kenneth H. Brown, Rosane Caetano, David Castle, Ruth Chadwick, Stephen Clarke, Karine Clément, Craig A. Cooney, Dolores Corella, Ivana Beatrice Manica da Cruz, Hannelore Daniel, Troy Duster, Sven O. E. Ebbesson, Ruan Elliott, Susan Fairweather-Tait, Jim Felton, Michael Fenech, John W. Finley, Nancy Fogg-Johnson, Rosalynn Gill-Garrison, Michael J. Gibney, Peter J. Gillies, Jan-Ake Gustafsson, John L. Hartman IV, Lin He, Jae-Kwan Hwang, Jean-Philippe Jais, Yangsoo Jang, Hans Joost, Claudine Junien, Mitchell Kanter, Warren A. Kibbe, Berthold Koletzko, Bruce R. Korf, Kenneth Kornman, David W. Krempin, Dominique Langin, Denis R. Lauren, Jong Ho Lee, Gilbert A. Leveille, Su-Ju Lin, John Mathers, Michael Mayne, Warren McNabb, John A. Milner, Peter Morgan, Michael Muller, Yuri Nikolsky, Frans van der Ouderaa, Taesun Park, Norma Pensel, Francisco Perez-Jimenez, Kaisa Poutanen, Matthew Roberts, Wim H.M. Saris, Gertrud Schuster, Andrew N. Shelling, Artemis P. Simopoulos, Sue Southon, E. Shyong Tai, Bradford Towne, Paul Trayhurn, Ricardo Uauy, Willard J. Visek, Craig Warden, Rick Weiss, John Wiencke, Jack Winkler, George L. Wolff, Xi Zhao-Wilson, Jean-Daniel Zucker
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- Journal:
- British Journal of Nutrition / Volume 94 / Issue 5 / November 2005
- Published online by Cambridge University Press:
- 08 March 2007, pp. 623-632
- Print publication:
- November 2005
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Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene–nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient–genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries.